Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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4,831 – 4,845 of 5,342 results

4,831

Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 500 MG

SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. This compound can be used for type 2 diabetes research.

Inhibits human TXNIP promoter activity and reduces TXNIP mRNA and protein levels in INS-1 cells.
Lowers glucagon secretion in TC1-6 cells and decreases glucagon secretion and action in vivo.
Reduces glucagon-induced glucose output from primary hepatocytes and blocks hepatic glucose output in vivo.
Reverses obesity- and Streptozotocin (STZ)-induced diabetes and hepatic steatosis in mice.
Orally bioavailable.
Well-tolerated in male C57BL/6J mice.

Pricing & Availability

4,832

Medchemexpress LLC Noscapine (hydrochloride) | 912-60-7 | 99.9% | 449.88 | 1 G

Noscapine (hydrochloride) is an orally active phthalideisoquinoline alkaloid with potent antitussive properties. It activates sigma opioid receptors and acts as a non-competitive Bradykinin inhibitor. This compound also disrupts microtubule dynamics, induces mitotic arrest and apoptosis.

Orally active phthalideisoquinoline alkaloid
Potent antitussive properties
Activates sigma opioid receptors and acts as a non-competitive Bradykinin inhibitor
Disrupts microtubule dynamics, induces mitotic arrest and apoptosis
Exhibits anticancer, neuroprotective, and anti-inflammatory activities
Can cross the blood-brain barrier

Pricing & Availability

4,833

Medchemexpress LLC Clorgyline hydrochloride | 17780-75-5 | 99.9% | C13H16Cl3NO | 100 MG

Clorgyline hydrochloride is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A) used in scientific research. It is structurally related to Pargyline. It has little effect on the amounts of conjugated dopamine (DA) in superfusate of slices from rat striatum. It contains an Alkyne group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. This product is for research use only, not sold to patients.

Irreversible and selective inhibitor of monoamine oxidase A (MAO-A)
Used in scientific research
Structurally related to Pargyline
Has little effect on conjugated dopamine (DA) in superfusate of slices from rat striatum
Contains an Alkyne group
Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups

Pricing & Availability

4,834

Medchemexpress LLC Clorgyline hydrochloride | 17780-75-5 | 99.9% | C13H16Cl3NO | 50 MG

Clorgyline hydrochloride is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A) used in scientific research. It has minimal effect on conjugated dopamine (DA) amounts in superfusates of rat striatum slices. This compound contains an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Irreversible and selective inhibitor of monoamine oxidase A (MAO-A)
Structurally related to Pargyline
Contains an Alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide groups
Increases nicotine infusions and motivation to obtain nicotine in rats at 2 mg/kg daily for 28 days
Pretreatment with 1 mg/kg intravenously for 1 hour has little effect on the efflux of conjugated dopamine (DA) and p-tyramine-evoked release of conjugated DA from slices of rat striatum

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4,835

Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | C14H14ClN3 | 100 MG

Fadrozole hydrochloride (CGS 16949A) is a potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. Intended for research use only, this compound effectively inhibits estrogen and progesterone production. It has demonstrated efficacy in preventing the development of various spontaneous neoplasms and reducing parasite burden in animal models.

Potent, selective, and nonsteroidal aromatase inhibitor
Inhibits estrogen production in hamster ovarian slices
Inhibits progesterone production
Prevents development of benign and malignant spontaneous mammary neoplasms
Reduces incidence of spontaneous hepatocellular tumors
Reduces parasite burden in male and female mice

Pricing & Availability

4,836

Medchemexpress LLC SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) | 125941-87-9 | 99.8% | 324.24 | 1 MG

SCH-23390 hydrochloride is a potent and selective dopamine D1-like receptor antagonist, also acting as a potent human 5-HT2C receptor agonist. It binds with high affinity to various serotonin receptors and inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels. This compound can reverse inhibitory effects on NLRP3 expression and inflammasome pathways in BV-2 cells, and has been used in studies of neurological disorders like psychosis and Parkinson's disease.

Potent and selective dopamine D1-like receptor antagonist
Potent and high efficacy human 5-HT2C receptor agonist
Binds with high affinity to 5-HT2 and 5-HT1C receptors
Inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels
Used in studies of neurological disorders like psychosis and Parkinson's disease

Pricing & Availability

4,837

Medchemexpress LLC Arg1-in-1 hydrochloride | 90.0% | C11H22BClN2O4 | 1 MG

ARG1-IN-1 hydrochloride is an orally active arginase inhibitor with an IC50 value of 29 nM. It can inhibit serum arginase activity and increase arginine levels in mouse tumor models, making it applicable for tumor research.

Orally active arginase inhibitor.
Inhibits serum arginase activity.
Increases arginine levels in mouse tumor models.
Applicable for tumor research.

Pricing & Availability

4,838

Medchemexpress LLC Slp7111228 hydrochloride | 1449768-48-2 | 98.0% | 5 MG

SLP7111228 hydrochloride is the hydrochloride salt of SLP7111228 supplied as a solid research reagent for biochemical assay use. It has formula C22H34ClN5O, molecular weight 419.99, and CAS 1449768-48-2. Store sealed at -20°C; in solution store at -80°C for long-term stability.

Hydrochloride salt form.
Solid, white/off-white appearance.
Molecular formula C22H34ClN5O.
Molecular weight 419.99.
CAS number 1449768-48-2.
Storage: -20°C; in solvent -80°C (6 months), -20°C (1 month).

Pricing & Availability

4,839

Medchemexpress LLC Proadifen (hydrochloride) | 62-68-0 | 99.9% | 250 MG

Proadifen (hydrochloride) | 62-68-0 | 99.9% | 250 MG

Pricing & Availability

4,840

Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 | C24H34ClN5O4S | 5MG

Yonkenafil hydrochloride is the hydrochloride salt of a selective phosphodiesterase 5 (PDE5) inhibitor supplied for research use. It is provided as a high-purity solid suitable for in vitro and preclinical studies involving PDE5-related pathways, neuroscience, and pharmacology. Typical solvent compatibility includes DMSO; follow the SDS and laboratory safety procedures.

High purity suitable for research.
Solid form for accurate weighing and formulation.
Soluble in DMSO for assay preparation.
Appropriate for in vitro and preclinical pharmacology studies.
Available in small-scale vials for dose-ranging experiments.

Pricing & Availability

4,841

Medchemexpress LLC (S,S,S)-AHPC hydrochloride | 2115897-23-7 | 99.2% | 467.02 | C22H31ClN4O3S | 5MG

(S,S,S)-AHPC hydrochloride is the hydrochloride salt of an AHPC-derived VHL ligand used as a building block and negative control in E3 ligase recruitment and PROTAC research. It facilitates the study of VHL-mediated ubiquitination and proteasomal degradation, and is supplied for synthetic and assay applications in small research quantities.

High purity 99.2%
Molecular weight 467.02
Chemical formula C22H31ClN4O3S
Solid white to yellow appearance
Suitable as a negative control and VHL ligand building block for PROTAC design
Available in small milligram pack sizes for research use

Pricing & Availability

4,842

Medchemexpress LLC DC-BPi-11 hydrochloride | 00-00-0 | 97.0% | C20H24ClN5O2S | 10MG

DC-BPi-11 hydrochloride is a research-grade small-molecule inhibitor of the bromodomain PHD finger transcription factor (BPTF) used in epigenetics and cancer research. It has demonstrated inhibition of leukemia cell proliferation and a reported IC50 of 698 nM against BPTF. The compound is supplied as a powder and analytical batch documentation reports a purity of 97.0%.

Inhibits BPTF with an IC50 of 698 nM.
Demonstrates inhibition of leukemia cell proliferation.
Supplied as a powder for handling and storage flexibility.
Powder stable at -20°C for up to 3 years.
High reported purity: 97.0%.
Chemical formula C20H24ClN5O2S; molecular weight 433.95.

Pricing & Availability

4,843

Medchemexpress LLC Gyki 53655 (hydrochloride) | 143692-48-2 | MFCD01941362 | 98.4% | 388.85 g·mol⁻¹ | C19H21ClN4O3 | 1 ML

GYKI 53655 hydrochloride is a selective, non-competitive antagonist of AMPA receptors used in electrophysiology and receptor pharmacology research. The hydrochloride salt is available as a high-purity solid or as a ready-to-use 10 mM solution in DMSO.

Selective non-competitive AMPA and kainate receptor antagonist.
Available as 10 mM solution in DMSO (1 mL) or as solid doses.
High purity (~98.4%) suitable for in vitro studies.
Molecular weight 388.85 g·mol⁻¹ and formula C19H21ClN4O3.
Recommended storage: solid at 4°C; solution at -80°C for long-term storage.

Pricing & Availability

4,844

Medchemexpress LLC Defactinib hydrochloride | 1073160-26-5 | 99.4% | 50 MG

Defactinib hydrochloride is the hydrochloride salt of defactinib (VS-6063; PF-04554878), a small-molecule focal adhesion kinase (FAK) inhibitor used in research to study FAK signaling, tumor cell motility, and antineoplastic and antiangiogenic mechanisms.

Inhibits FAK phosphorylation at Tyr397 in a time- and dose-dependent manner.
Hydrochloride salt form, off-white powder suitable for research use.
Molecular formula C20H22ClF3N8O3S; molecular weight 546.95 g/mol.
Reported purity 99.35% with available certificate of analysis.
Available in multiple pack sizes, including 50 mg.
Supporting documents available: data sheet, COA, and SDS.

Pricing & Availability

4,845

Medchemexpress LLC Acotiamide hydrochloride | 185104-11-4 | 99.6% | 25 MG

Acotiamide hydrochloride is the hydrochloride salt of acotiamide, provided as a research-grade solid reagent used to study gastric motility, delayed gastric emptying, and related gastrointestinal disorders. It is supplied in small pack sizes with high reported purity suitable for analytical and in vitro research.

Orally active, reversible acetylcholinesterase inhibitor (reported IC50 ~1.79 μM).
Hydrochloride salt for improved stability and solubility.
High reported purity for research applications (reported ~99.6%).
Molecular formula C21H31ClN4O5S; molecular weight 487.01.
Available in small research pack sizes such as 25 mg.

Pricing & Availability

Alcohols and polyols

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Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Noscapine (hydrochloride) | 912-60-7 | 99.9% | 449.88 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Clorgyline hydrochloride | 17780-75-5 | 99.9% | C13H16Cl3NO | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Clorgyline hydrochloride | 17780-75-5 | 99.9% | C13H16Cl3NO | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | C14H14ClN3 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) | 125941-87-9 | 99.8% | 324.24 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Arg1-in-1 hydrochloride | 90.0% | C11H22BClN2O4 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Slp7111228 hydrochloride | 1449768-48-2 | 98.0% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Proadifen (hydrochloride) | 62-68-0 | 99.9% | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 | C24H34ClN5O4S | 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (S,S,S)-AHPC hydrochloride | 2115897-23-7 | 99.2% | 467.02 | C22H31ClN4O3S | 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC DC-BPi-11 hydrochloride | 00-00-0 | 97.0% | C20H24ClN5O2S | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Gyki 53655 (hydrochloride) | 143692-48-2 | MFCD01941362 | 98.4% | 388.85 g·mol⁻¹ | C19H21ClN4O3 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Defactinib hydrochloride | 1073160-26-5 | 99.4% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Acotiamide hydrochloride | 185104-11-4 | 99.6% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More